Knockdown of DcR3 to treat endometriosis

Knockdown of DcR3 to treat endometriosis

A news conference was held on November 10, 2017, by the Genomics Research Center of the Academia Sinica to announce a possible treatment of endometriosis by suppressing the expression of DcR3 or Decoy receptor 3 which promotes cell adhesion and enhances endometriosis development.

It has been found that DcR3 suppression level was the most significant parameter associated with endometriosis severity.  DcR3 promotes growth and spreading of the endometrium.  Knockdown of DcR3 reduced cell adhesion and migration, and inhibited ectopic adhesion of the endometrium, and abrogated endometriosis progression.  It is found that DcR3 plays a critical role in the pathogenesis of endometriosis and inhibition of DcR3 expression provides a promising approach for the treatment of endometriosis.  This study has been published on October 23 in the Journal of Pathology.

 

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About masterchensays

Victor Chen, herbalist, alternative healthcare lecturer, Chinese affairs analyst, retired journalist
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